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The three highly homologous human RUNX TFs (RUNX1, 2, and 3) have been implicated in developmental processes and, notably, in cancer.
PBDEs/OH-PBDEs have been implicated in developmental neurotoxicity.
Differential DNA methylation has been implicated in developmental outcomes of early-life nutrient restriction [ 34].
Members of the CCN family have been implicated in developmental processes such as chondrogenesis, osteogenesis, and angiogenesis.
PCBs are neurotoxic and have been implicated in developmental problems, so detection of PCBs in children is of particular concern.
Autophagy has also been implicated in developmental tissue remodeling and differentiation and has been proposed as a mechanism of cell death in breast luminal cell clearance 9, 11.
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KLFs are implicated in developmental as well as pathologic vascular processes.
Among 31 TFs that had significant 8-mer matches, 28 were implicated in developmental processes and many were homeobox TFs.
Three converging lines of evidence have suggested that cerebellar abnormality is implicated in developmental language and literacy problems.
In Arabidopsis, LUG and TOPLESS (TPL) are the most studied Gro/Tup1 co-repressors that are implicated in developmental processes and hormone signaling [ 9, 12, 13].
Thirty percent of the target genes were implicated in developmental processes, and more than half of the targets from this group were involved in neuronal development [ 44].
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