A similar observation has been made in clinical isolates of Enterococcus faecium in which IS elements were implicated in developing new subspecies that are better adapted to a hospital environment [ 23].
As a neuronal guidance molecule, netrin-1 has been implicated in the developing brain Previous studies have found high expression levels of netrin-1 in the intestine, including in patients with inflammatory bowel disease (IBD) Netrin-1 has been implicated in immune functions At present, the functional role of netrin-1 in IBD is unknown.
To clarify the molecular mechanisms of Spn-F retention we focused on Jvl, which is reported to interact with Spn-F and has been implicated in IKKε polarization in developing oocytes (Dubin-Bar et al., 2011; Amsalem et al., 2013).
Sonic hedgehog (Shh), a vertebrate homolog of the Drosophila segment polarity gene hedgehog (hh), has been implicated in patterning of the developing chick limb.
Finally, vitamin D deficiency has been implicated in the likelihood of developing a variety of autoimmune diseases including insulin dependent diabetes mellitus, rheumatoid arthritis, experimental autoimmune encephalomyelitis (EAE), and inflammatory bowel disease [53], [54], [57].
38, 41 This may be analogous to the overlapping pathogenetic pathways underlying obesity and type 2 diabetes, where the fat mass and obesity-associated gene has been implicated in the propensity to developing both obesity and diabetes.
In doing so, we argue that investigations of the nature of attachment styles in psychosis and how they relate to the cognitive, interpersonal and affective factors that have been implicated in psychosis will help develop theoretical knowledge in relation to the condition.
RRRAA or ESRRAL have been implicated in the susceptibility to develop RA.
Not only did his work introduce the concept of congenital rubella syndrome (CRS) as a specific entity, it marked the first time an environmental agent had been implicated in causing damage to a developing conceptus.
The FGF pathway has previously been implicated in inducing chondrogenesis in the developing facial prominences (Abzhanov and Tabin, 2004).
Other pathways that have been implicated in SOX2 regulation in the developing lung, including FGF10, WNT/beta-Catenin signaling, and TTF1 (Que et al., 2007; Gontan et al., 2008; Hashimoto et al., 2012), had relatively modest effects on its induction following erlotinib treatment in EGFR-mutant cancer cells, pointing to FOXO6 as the dominant pathway in this model of oncogene-dependent signaling.
