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While tamoxifen has been implicated in decline in cognitive function (Paganini-Hill and Clark, 2000), these data do not come from double-blind randomised placebo-controlled trials, and so the issue remains controversial.
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Seagrass leaves are often densely covered by epiphytic algae which can suppress seagrass productivity and has been implicated in declines of seagrass meadows worldwide.
Bacteria have also been implicated in declining coral health.
Furthermore, parasites have been implicated in declines of natural and commercial pollinators, such as bumblebees, worldwide [ 25, 46, 47], and thus knowledge of genes and pathways involved in immunity and parasite defence is highly important.
Reduced availability of NO, important for angiogenesis and maintenance of endothelial integrity, together with increased generation of O2−*, a marker of inflammation and mediator of atherosclerosis, are implicated in decline of vascular function in diabetes [4] [7].
Advancing age is associated with reductions in nitric oxide bioavailability and changes in metabolic activity, which are implicated in declines in motor and cognitive function.
In a study of older rats, van Praag et al. 2005 [ 75] found that those that exercised on a running wheel showed a reversal in declines of neurogenesis (decline in neurogenesis has been implicated in cognitive decline).
High soil aluminum and low soil calcium concentrations resulting from acid deposition have been implicated in this decline.
European officials plan to vote on a proposal to sharply restrict the use of chemicals that have been implicated in the decline of global bee populations.
9.21am GMT Welcome to the Eco Audit Today, European officials are set to vote on a proposal that would see a group of insecticides known as neonicotinoids, which have been implicated in the decline of bees, largely outlawed across the continent.
Introduction of invasive species has been implicated in the decline of many native species.
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