However, heme and hemoproteins have been implicated in controlling the expressions of cell cycle regulators and cell growth in mammals.
Additionally, we use CRISPRs to generate cos2/kif7mw406, a mutation in the kinesin-4 family member cos2/kif7 that has been implicated in controlling ciliary architecture and Hedgehog signaling to test whether it may be functioning redundantly with osm-3/kif17.
Oxygen concentration has been implicated in controlling oligodendrocyte progenitor proliferation and survival [43].
The latter has also been implicated in controlling angiogenic sprouting [11].
Similarly, chemokines have been implicated in controlling HSC/HPC homing [1].
Both molecules have been implicated in controlling Treg cell migration [41], [43], [44].
Oncogenic RAS through RAF/MEK/ERK and PI3K-AKT have been implicated in controlling VEGF expression [27].
Since the Toll and Jak-Stat pathways have also been implicated in controlling viral infections in Drosophila, we finally investigated if these pathways affect the Nora virus.
In mice, retinoic acid (RA) signaling has been implicated in controlling entry into meiosis in germ cells, as meiosis in male embryonic germ cells is blocked by the activity of a RA-catabolizing enzyme, CYP26B1.
We have demonstrated a central role of Shaw K+ channels for coordinated and rhythmic output from clock neurons in Drosophila, which seems to be conserved in mammals, where homologues of Shaw have also been implicated in controlling circadian behavior [21].
