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Overproduction of cytokines has been implicated in chronic fatigue syndrome.
The human pathogen Chlamydia pneumoniae has been implicated in chronic inflammatory diseases including type 2 diabetes.
Low-grade systemic inflammation has been implicated in chronic pain, as well as in comorbid diseases like depression and fatigue.
Here, we review the genetic variants that have been implicated in chronic pain conditions, divided into the following etiologically-grouped categories: migraine, musculoskeletal pain disorders, neuropathic pain disorders, and visceral pain disorders.
The novel human gammaretrovirus xenotropic murine leukemia virus-related virus (XMRV), originally described in prostate cancer, has also been implicated in chronic fatigue syndrome (CFS).
Recently, the xenotropic murine leukemia virus-related virus (XMRV) has been implicated in chronic fatigue syndrome (CFS) and in prostate cancer by several, though not all studies.
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The plasma proteins are implicated in chronic diseases, inflammation, endothelial function and metabolic signaling.
Altered mucosal expression of hBDs has been suggested to be implicated in chronic inflammatory bowel disease pathogenesis.
The set of proteins present on the assay consists of factors that are implicated in chronic diseases, inflammation, endothelial function and metabolism.
Previously, miR-29a was implicated in chronic lymphocytic leukaemia, cholangio carcinoma and lung cancer by deregulation of its target gene Tcl1 and DNMT3 as a tumor suppressor [11], [12].
In mammals, the kainate receptors are implicated in chronic pain regulation [ 53].
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