Sentence examples for been implicated in changes from inspiring English sources
Polyprotein positions 663, 710 and 729 have previously been implicated in changes in cell tropism34, and also in virulence15.
Recently, quasispecies heterogeneity per se has also been implicated in changes in virulence (Kenney et al. 2011; Sauder et al. 2006).
Notably, the loss of JAM-A has been implicated in changes to intestinal permeability with subsequent inflammation, cytokine production and colitis in mice (Laukoetter et al., 2007) and IBD in humans (Vetrano and Danese, 2009; Vetrano et al., 2008).
Differences in titin isoforms have been implicated in changes in length-dependent activation (17), but these changes are too slow to form part of an acute response, although they may contribute to apical ballooning in the case of preexisting conditions.
While we observed signals of cardiotoxicity for manganese, we did not observe an effect for nickel, which has previously been implicated in changes in heart rate and HRV [ 17].
Two main mechanisms have been implicated in changes of genome size: one is the accumulation of transposable elements [ 13, 14]; the other is the accumulation of tandemly repetitive sequences [ 15].
Additionally, the three CXCL9-11 polymorphiseemseem to be implicated in changes in the chromatin state in several immune-related cell lines.
Disease associated alterations in the phenotype of lamina cribrosa (LC) cells are implicated in changes occurring at the optic nerve head (ONH) in glaucoma.
An additional copy of Bna.FUL was implicated in changes in all three traits, further suggesting that this gene may represent a general adaptation factor.
It is likely that changes at the molecular level, such as extensive protein cross-linking and/or formation of high-molecular weight protein aggregates, may be implicated in changes to lens physical properties such as hardening and decreased compliance[ 1, 62] as well as in fiber compaction, since protein aggregation alters the interactions between cytoplasmic proteins and membranes [ 63].
The factors involved are numerous, and the chemistry of the entire system that forms the artwork is implicated in change, as demonstrated in this work by the role of pH of the substrate on different forms of cochineal-based colorants.
