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Seven of these genes (TPM1, CALD1, CTTN, FN1, CD44, ITGB4 and SLC3A2) have previously been implicated in cancers, and, in five cases, specific splice variants are correlated with the cancerous state.
The active form of vitamin D (1,25(OH)2D3) reduces proliferation and promotes differentiation, and has been implicated in cancers of the colon, breast and prostate.
Many of the genes in the signature have been implicated in cancers.
Human endogenous retroviruses have also been implicated in cancers and autoimmune diseases.
There are other translocations that have been implicated in cancers and other genetic diseases, and more are being discovered every day.
Both WWOX and FHIT have been implicated in cancers that are strongly associated with environmental carcinogens such as smoking and alcohol consumption.
Similar(47)
In test tubes, anthocyanins are highly effective in neutralizing free radicals, which have been implicated in cancer and various other diseases.
Notably, several HDACs have been implicated in cancer.
Several neuronal guidance molecules have been implicated in cancer invasion and metastasis (Ballard and Hinck, 2012).
Many of the targets identification techniques used here have previously been implicated in cancer [40, 41].
Inflammatory responses and associated products have been implicated in cancer metastasis.
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