Sentence examples for been implicated in biliary from inspiring English sources
Additionally, they have been implicated in biliary system diseases and to modify the excretion of other drugs through bile.
Multiple risk factors have been implicated in the development of biliary strictures, which could be categorized into recipient, graft, operative factors, and postoperative factors.
Activating BRAF gene mutations in the Raf/MEK/ERK pathway have been implicated in the development of biliary cancers and could represent a potential therapeutic target (Tannapfel et al, 2003).
Furthermore, K- ras has been implicated in aggressive ICC downstream of the biliary tree with increased expression levels in metastatic lymph nodes [ 121]; therefore K- ras expression correlates to poor prognosis [ 122].
Many of these genes have been previously characterized to function in lipid and carbohydrate metabolism or biliary transport, but few have been implicated in liver disease specifically (Chambers et al., 2011).
Based on its dual function in biliary bicarbonate secretion and anti-inflammatory effects in macrophage/Kupffer cells [37] the G protein-coupled bile acid receptor 1 (GPBAR1) TGR5 has been implicated in PSC pathogenesis.
