Sentence examples for been implicated in altering from inspiring English sources
More recently, Myc deregulation has been implicated in altering cellular metabolism, particularly by inducing both the Warburg effect and a reliance on exogenous glutamine [18], [25], [49].
The PI3K/AKT signaling pathway has also been implicated in altering breast cancer response to multiple therapies [1], [10], [11], [14].
The electrostatic properties of helix macrodipoles have previously been implicated in altering the reactivity (significantly reducing the pKa) of cysteine residues positioned at the N-termini of α-helices [30].
Whereas the low levels of hypophosphorylated RB1 reported for other Lmna/LMNA deficient cells have been implicated in altering the G1/S transition, our findings with LmnaDhe/+ fibroblasts suggest that the influence of RB1 extends to mitosis as well [11], [19], [26], [28], [39] [42].
CIA1 is a yeast gene that has not been implicated in altering yeast prion propagation.
Besides TNF α, several other cytokines have been implicated in altering intestinal permeability.
Indeed modulation of the expression of all of these transcription factors - E12 [ 35]; FREAC2 [ 36, 37]; FOXO4 [ 38]; LEF1 [ 39]; NFAT [ 40]; GATA4 [ 41]; ETS2 [ 42] have been implicated in altered gene expression during EMT.
In light of the current data set, we propose that a non-canonical mechanism (perhaps associated with metabolic dysfunction) is implicated in altering the calcium regulation in LCR myocytes thus giving rise to the contractile dysfunction observed in these hearts.
Growing evidence indicated that cytokines are involved in the pathogenesis of PE and interleukin-4 VNTR polymorphism could be implicated in altering the PE risk.
Therefore, HDACs may be implicated in altered gene expression profiles in the medial hypothalamus under different metabolic states.
The Ras pathway has also been implicated in cytoskeletal rearrangements, altering the expression of integrins and cell migration through activation of the PI3-K/Akt pathway (Potempa and Ridley, 1998; Okudela et al, 2004; Fleming et al, 2005).
