Sentence examples for been implicated in alterations from inspiring English sources
TBR1 has been implicated in alterations in the brain that may lead to Alzheimer's Disease (AD) and Parkinson's Disease (PD).
BPA has been classified as an endocrine disruptor and has been implicated in alterations in tissue enzyme and hormone receptor levels, interaction with hormone response systems, and cellular changes suggestive of carcinogenic potential (vom Saal et al. 2007).
Increased intracellular polyamines have been implicated in alterations in histone acetyltransferases and HDACs, potentially resulting in epigenetic changes that lead to the initiation and progression of tumours in a transgenic mouse model where ODC, the target of DFMO, is overexpressed [ 44– 44].
KLF-5 is implicated in alterations in VSMCs during the change to the synthetic phenotype, which includes alterations in gene expression, at the site of vascular injury.
Although several bacteria are implicated in alterations of host cell DNA methylation [ 23], this is the first demonstration that infection by an intracellular bacterium alters host DNA methylation patterns on a genome-wide scale.
However, it has been shown by others (Weidema et al, 2001), that activation of P2X4-receptors does not necessarily influence [Ca2+]i but is implicated in alterations of intracellular sodium concentrations ([Na+]i).
Among different neurotransmitters, serotonergic alterations have been implicated in cognitive alterations, and low extracellular serotonin levels seem to be associated with impaired learning and memory consolidation (Ramos-Rodriguez et al., 2013).
The methylation and acetylation of lysine residues in histones by specific histone methyltransferases (HMTs) [17] and histone deacetylase (HDACs) [18] have been implicated in the alterations of chromatin structure and gene regulation.
10 Indeed, these species and free radicals have been implicated in mucosal alterations in gastric or intestinal injuries.
Arsenic has been implicated in promoting alterations in multiple cellular pathways, including growth and proliferation pathways, apoptotic pathways, DNA repair mechanisms, immunosurveillance, and stress response pathways (Rossman 2003).
