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Dysregulation of microRNAs (miRNAs) has been implicated in almost every known survival mechanisms utilized by cancer cells.
In most cases, the etiology is bacterial, although viruses have been implicated in almost 9% of cases [ 17].
MMP activity has been implicated in almost every stage of the metastatic cascade from the primary site to the progression of tumor-extravasation,- growth and -development.
Wnt-5a is one of the most highly investigated non-canonical Wnts and has been implicated in almost all aspects of non-canonical Wnt signalling.
Not surprisingly, miRNA have been implicated in almost all biological processes including cellular growth, differentiation, apoptosis, and even neurodevelopmental processes such as dendritic spine development and synaptic plasticity [ 7, 8].
PPARγ has been implicated in almost all of the pathological processes contributing to atherosclerosis, including endothelial dysfunction, leukocyte chemotaxis, foam cell formation, and plaque evolution, destabilization, and rupture (32).
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Smoking remains the biggest preventable cause of cancer and is implicated in almost one in five cases.
Buckfast tonic wine has a reputation in Scotland for being linked to violence – and it has emerged that it was implicated in almost 450 violent crimes over the past three years – but that reputation is rather muddled.
According to a report written in 2010 by John Hart, an American scientist and one of the top elephant researchers in Congo, the "Congolese military are implicated in almost all elephant poaching," making the military "the main perpetrator of illegal elephant killing in D.R.C".
According to a report written in 2010 by John Hart, an American scientist and one of the top elephant researchers in Congo, the "Congolese military are implicated in almost all elephant poaching," making the military "the main perpetrator of illegal elephant killing" in Congo.
Opioid overdose deaths are at a record high in the U.S., and deaths from prescription painkillers, including oxycodone, hydrocodone and methadone, are implicated in almost half of all cases.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com