Sentence examples for been implicated in activating from inspiring English sources
Extracellular Hsp90α has been implicated in activating a number of proteins important for disease- relevant processes [38].
Furthermore, dynamic motion of G0-glycosylated antibodies has been observed by NMR, and increased carbohydrate exposure has been implicated in activating the complement system via interactions with the mannose-binding lectin (MBL) [28], [29].
The latter have been implicated in activating a mutated or promiscuous androgen receptor, if present [ 43, 44].
On the contrary, HP1γ has also been implicated in activating gene expression through its association with elongating RNA polymerase II [ 54, 55].
It may be relevant that acidic residues have been implicated in activating the catalytic water in further dimer-forming GTPases, MeaB [ 33], MnmE [ 34] and HypB [ 40], as also in related ATPases, Soj [ 39] and Av2 [ 41].
Multiple stress stimuli have been implicated in activating apoptosis in cardiomyocites eventually leading to heart failure, these include: excessive mechanical stress, ROS, β1 adrenergic receptor agonists, angiotensin II, cytokines.
However, the Pagano lab recently showed that hCdc14B is implicated in activating APC/CCdh1 in G2-phase in response to DNA damage [59].
We showed that depletion of SOCS3 reduced the EBV-mediated suppression of the IFNα pathway and that the EBV protein Zta (also known as ZEBRA) was implicated in activating SOCS3 expression.
Indeed, it has been shown that intracellular AGEs are implicated in activating intracellular signalling pathways as well as in modifying the function of intracellular proteins, thereby contributing to diabetic vascular complications (Brownlee 2005).
This model is attractive because RPA plays an essential role in initiating NER and also is implicated in activating ATR (see above).
Our results showed that both the MDR1 mRNA and P-gp expression increased after CH co-incubated with SP600125 in K562/ADR cells, suggesting CH induced MDR1 mRNA and P-gp expression down-regulation is implicated in activating JNK.
