Sentence examples for been implicated based on from inspiring English sources

Although the role of Fabp7 in fatty acid delivery during development is not clear, its involvement in cell growth and differentiation has been implicated based on its influence on cell morphology [3].

Interestingly, C5 has already been implicated, based on studies conducted in mice [ 12- 14], and it should therefore be considered an equally likely candidate.

Antibody-dependent enhancement (ADE) has also been implicated, based on observations that re-infection by a different viral serotype increases the risk of severe dengue [ 31].

The specific cell receptors that Cry1F toxins interact with and lead to subsequent toxicity have yet to be identified for O. nubilalis [ 11], although cadherin and aminopeptidases have been implicated based on ligand blot assays [ 12, 13].

Numerous non-infective agents have been implicated based on epidemiological studies but none have stood up to scrutiny. 1 3 5 The focus over the past two decades has been on infective agents that might trigger sarcoidosis, with the strongest suspects found in the mycobacteria family and the common commensal P acnes.

We used the MetaCore transfactor analysis tool to determine which transfactors could be implicated based on published data.

How RA is initiated is unclear, but T-cell responses to self-antigens are implicated based on the strong linkage of RA to particular MHC alleles.

Possible therapeutic strategies to target redox-sensitive signaling molecules, transcription factors, or cofactors are implicated based on the updated view of ROS-mediated regulation of inflammatory target genes in brain inflammation and neurodegenerative disorders.

These cells have been implicated in amyloidogenesis based on their close ultrastructural relationship with amyloid deposits [31], [32], phagocytic function [33], and their proteolytic enzymes [34].

Sro7p and Sro77p have been implicated in secretion based on genetic studies demonstrating decreased secretion of invertase and an accumulation of secretory vesicles in the absence of SRO7 and SRO77 [19].

The phosphatidylinositol 3-kinase (PI3K) pathway has long been implicated in aging based on the demonstration that attenuating insulin/IGF1/FOXO activity extends lifespan in C. elegans [ 27].