Sentence examples for been implicated as targets from inspiring English sources

GABA systems have been implicated as targets for ethanol at the cellular, molecular and behavioural level.

Both MSP-1 and AMA-1 have been implicated as targets of SSPI in Plasmodium falciparum malaria in humans [23] [28] and in Plasmodium chabaudi malaria in rodents [29] [31].

Numerous tumor-suppressor genes have been implicated as targets for methylation in other cancers (Cairns 2004; Kim et al. 2004; Roman-Gomez et al. 2004).

We chose to study the histone modifications on promoters of BDNF (Fig. 1) and DLX5, two genes that have been implicated as targets of MeCP2, the products of which play important roles in normal neuronal development.

Thermolysin-like metalloproteases are recognized to be responsible for a number of symptoms associated with severe infections such as increase of vascular permeability, hemorrhagic edema, sepsis and necrotic tissue destruction in infected humans, and have therefore been implicated as targets for the development of second generation antibiotics [ 56].

We report protein level changes in the striatum and in the hippocampus, both of which are part of the developing cholinergic and catecholaminergic systems that have been implicated as targets for some PBDEs (Mariussen and Fonnum 2003; Meerts et al. 2004; Viberg et al. 2002, 2003a, 2004b).

G4 DNA structures are implicated as targets in telomere maintenance, and helicases that unwind G4 DNA are closely associated with telomere stability.

CA enzymes are implicated as targets of variable drug therapeutic classes and the discovery of selective, drug-like CA inhibitors is essential.

Furthermore, protein secretion related proteins were implicated as targets of posttranscriptional regulation since their protein abundance appeared to be differentially expressed, while the transcript abudance was not (Table 3, Figure 6).

A diverse set of biomarkers have been implicated as immunotherapeutic targets and prognostic indicators in other cancers.

At the transcriptional level, Eph receptors and ephrin ligands have been implicated as downstream targets of many different transcription factors, including homeodomain proteins [13] and the p53 protein family [14], [15], [16], [17].