Sentence examples for been implicated as potent from inspiring English sources
Effector CD4 T cell lineages have been implicated as potent inducers of autoimmune diseases.
Furthermore, PGE2 has been recently identified to promote naive T cell differentiation to IL-17 – producing T helper (Th17) cells, a subset of T helper cells which have been implicated as potent effector cells in IBD [33].
Fatty acids have been implicated as potent inducers of adipogenic genes in mammalian [ 28, 29] and chicken [ 7, 10] preadipocytes.
Interleukin-6 and tumor necrosis factor-α have been implicated as potent negative regulators of lipoprotein metabolism in vitro [ 12, 13] and in vivo [ 14, 15].
GRP78 are Ca2+-binding proteins in the ER, the intracellular Ca2+ levels have been implicated as potent regulators in the expression of the GRP78.
This led to an increase in reactive oxygen species, which have been implicated as potent triggers of apoptosis and retinal ganglion cell loss in LHON (Yu-Wai-Man et al., 2009).
Among them, ET-1, derived from cerebral arteries endothelial cells, has been implicated as a potent vasoconstrictor in mediating SAH-induced vasospasm.
Although the signaling mechanisms involved in anoikis resistance are still not completely understood, it has long been implicated as a potent target for cancer treatment due to its crucial importance for metastasis.
LTB4 is a known potent inflammatory mediator and has been implicated as a probable cause of chronic ocular inflammation and retinopathy in diabetes [ 34] and has also been held responsible for the development and progression of experimental autoimmune uveitis [ 35].
Recently, VEGF, which, as noted above, is a potent vascular permeability and angiogenic factor, has been implicated as an additional explanatory factor that determines MR signal enhancement although the relationship between MRI enhancement and tissue VEGF expression is not straightforward.
Gallic acid and tannins from A. rubrum leaves have been implicated as the toxic compounds responsible for Red Maple Toxicosis (Boyer et al, 2002), but this study found that pyrogallol is a more potent inducer of methemoglobinemia.
