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Appalachian USA coal mines have been implicated as major stressors to aquatic life in headwater streams via discharge of total dissolved solids (TDS).
The photochemical screening of MZO indicated the presence of phenols, tannins, alkaloids, saponins, glycoside, terpenoids, anthraquinone, flavonoids (Table 1), which have been implicated as major antioxidants and antimicrobial bioactive compounds from natural products.
Midbrain dopaminergic neurons, especially in the mesolimbic system has been implicated as major candidates to mediate incentive salience in the natural reward pathway.
A history of sexually transmitted infection (STI) and pelvic inflammatory disease have been implicated as major risk factors for EP.
Aflatoxin exposure and hepatitis B virus infection have been implicated as major risk factors for primary hepatocellular carcinoma (PHC) in high-incidence regions of the world.
Several members of the galectin family have been shown to have profound effects on cell survival and they have been implicated as major regulators of inflammatory responses [ 29].
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IL-6 is implicated as major regulators of glioma cell growth and invasiveness.
Evidence indicates that both endocrine and environmental factors play mechanistic roles in female breast cancer (Bray et al. 2004), and estrogenic hormones are implicated as major determinants of breast cancer risk (Bernstein 2002; Bray et al. 2004).
Glyphosate, which is an herbicide, is not as toxic for birds and has not been implicated as a major cause of raptor decline.
Native state topology has been implicated as a major determinant of protein-folding mechanisms.
Biofilms have been implicated as the major cause of various chronic infections.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com