Sentence examples for been implicated as essential from inspiring English sources

In M. tuberculosis, both TS enzymes have been implicated as essential for growth, either based on drug-resistance studies or genome-wide mutagenesis screens.

Both STAT1 and STAT3 proteins have been implicated as essential components linking cytokines signals to transcriptional events in pathogenesis of liver disease [ 12, 16, 29].

Although TRPC3 and TRPC6 channels have been implicated as essential elements mediating calcium and growth responses of neonatal cardiomyocytes to Ang II [ 34], their role in adult myocytes remained unexplored.

Accordingly, DOT1L expression and function and concomitant mitotic increases in H3K79me2 are implicated as essential components required to maintain genome stability in human cells.

By extension, the psychologists who are members of the association are implicated as well.

Boron, for example, has been demonstrated to be required for the growth of many perhaps all higher plants but has not been implicated as an essential element in the nutrition of either microorganisms or animals.

Pathogen mediated PI3K activation, in particular, has been implicated as being essential to phagocytosis induction [13] [16].

This protein is found in cytosolic complexes containing gamma-tubulin and CRM-1 in hepatoma cells and has been implicated as an essential constituent of centrosome assembly [27].

Catalase has been implicated as an essential defense against the potential toxicity of hydroxyl radicals.

Moreover, VEGF enhances vascular permeability to water and large molecular weight proteins [ 36], a process in which p38 MAPK pathway has been implicated as an essential mediator [ 37].

AGOs have been implicated as proteins essential in the gene regulatory mechanisms fundamental to developmental and cellular processes such as mRNA stability/degradation, protein synthesis, and genomic integrity [ 4, 6, 8].