Sentence examples for been implicated as drivers from inspiring English sources
What's more, the seasonal fluctuations in social connectivity produced by school holidays have been implicated as drivers of the seasonal and supra-annual cycling of childhood respiratory diseases [7], [11], [12], which, in developing countries, are the leading cause of mortality amongst children under five years of age [13], [14].
Both H3K9Me3 and H3K27Me3 marks are associated with gene silencing and have been implicated as drivers of other chromatin changes, including histone deacetylation and DNA methylation.
These factors combine to severely compromise health workers' abilities to deliver adequate quality care and have been implicated as drivers of disrespectful intrapartum care [ 10].
Furthermore, downstream targets of MYC oncogene and tumor-promoting microRNAs have also been implicated as drivers of medulloblastoma dissemination [ 17, 18].
Trait-mediated interactions may be particularly relevant in parasite host systems because parasites frequently modify host behaviour or physiology [ 6, 7] and have been implicated as drivers behind a range of biological invasions, including wild oat (Avena fatua) in California, fire ants (Solenopsis invicta) in North America and amphipod crustaceans (Gammarus) in UK freshwaters [ 6, 8].
The myofibroblast cell type has been implicated as a driver of tumor progression [ 21].
Notably, overexpression of X linked genes has been implicated as a driver of tumorigenesis [ 92, 93].
MSP expression has recently been implicated as a driver of breast cancer metastasis and is a marker of poor prognosis [ 36].
Such a pathway may not be exclusively limited to breast cancer [ 20], given that deregulated Notch signaling has been implicated as a driver of disparate malignancies [ 15], as promoting aberrant cell cycle progression [ 41], and associated with unfavorable outcome [ 18].
In mantle cell lymphoma (MCL), deregulation of the CCND1 locus is prognostic and has been implicated as a driver of disease onset, but is dispensable for disease progression (Bertoni et al, 2006; Gladden et al, 2006).
Cyclin D1 upregulation has been implicated as a driver of gastric cancer, and its inhibition has been shown to reverse the transformed phenotype of human gastric cancer cells (Chen et al, 1999).
