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Inflammatory injury and induction of oxidative stress have been implicated as causative factors in neurodegenerative diseases such as Alzheimer's disease (AD).
Overall, the commensal yeast Candida albicans is the most common fungal isolate in patients with endogenous fungal endophthalmitis, although other Candida strains have been implicated as causative organisms including Candida tropicalis, Candida parapsilosis, Candida glabrata, Candida guilliermondii, Candida krusei, and more recently Candida dubliniensis [1].
Circulating TNF-α and MCP-1 are increased in obesity and have been implicated as causative factors in obesity-associated insulin resistance and the development of type 2 diabetes [13], [17] [20].
Whereas cilia damage and reduced cilia beat frequency have been implicated as causative of reduced mucociliary clearance in smokers, theoretically mucociliary clearance could also be affected by cilia length.
While large numbers of genes have been implicated as causative of ASD, we next discuss data suggesting that a common theme in ASD etiology may be alterations in cellular secretory pathway(s).
Haploinsufficiency of one of these genes, SATB2, a DNA-binding protein that regulates gene expression, has been implicated as causative in the cleft or high palate of individuals with 2q32q33 microdeletion syndrome.
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Human papillomavirus (HPV) infection has been implicated as a causative factor of cervical cancer.
Several members of the cysteine protease family of enzymes have been implicated as possible causative agents in a variety of diseases.
Marijuana smoking has been implicated as a causative factor in traditionally tobacco-related tumors of the head and neck and of the lung.
Sleep deficiency, with its negative impact on performance, also has been implicated as a causative factor in several public disasters (e.g., crash of Colgan Air Flight 3407 in Buffalo, N.Y).
Human papillomavirus (HPV) is a common sexually transmitted infection (STI) and has been implicated as a causative agent of anogenital cancers including cervical, vaginal, vulvar, and anal cancer [1], [2].
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been suspected as causative
been searched as causative
been established as causative
been incriminated as causative
been confirmed as causative
been discounted as causative
been reported as causative
been considered as causative
been recognized as causative
been determined as causative
been discerned as causative
been identified as causative
been recognised as causative
been proposed as causative
been implicated as causal
been implicated as etiological
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