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Specifically, microRNAs have been identified to regulate cell cycle through regulation of cyclin G1 [ 8].
Besides the mainstreams of transcriptional and hormonal regulations, various mechanisms have been identified to regulate browning that include cytoskeleton remodeling (McDonald et al. 2015), circadian rhythm (Gerhart-Hines et al. 2013), microRNAs (Kim et al. 2014), long non-coding RNAs (Alvarez-Dominguez et al. 2015), and the central nervous system (Liu et al. 2012; Hankir et al. 2016).
An increasing number of miRNAs have been identified to regulate osteoblast differentiation and bone formation positively by targeting negative regulators of osteogenesis or negatively by targeting important osteogenic factors.
MicroRNAs are increasingly being recognized as regulators of embryonic development; however, relatively few microRNAs have been identified to regulate cardiac development.
Among these target miRNAs of Lrrc75a-as1, miR-29a-3p has been identified to regulate VSMC calcification by targeting ADAMTS-739, while the miR-24 family members have been reported to have significant function in cardiovascular diseases40.
In mouse hepatocytes and rat liver, iron status has been identified to regulate MDM2, which is associated with specific changes in p53 expression (Dongiovanni et al., 2010).
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Based on transcriptome comparison between red- and green-colored leaves, an MYB transcription regulator PpMYB10.4 in the Gr interval was identified to regulate anthocyanin pigmentation in peach leaf.
A diverse set of host gene networks was identified to regulate Wolbachia levels and unexpectedly revealed that perturbations of host translation components such as the ribosome and translation initiation factors results in increased Wolbachia levels both in vitro using RNAi and in vivo using mutants and a chemical-based translation inhibition assay.
Recently, two LRR-RLKs, BIR1 and SOBIR1, were identified to regulate cell death and innate immunity in Arabidopsis [ 27].
In addition to these four genes, here we identified several homologues of transcription factor genes that were identified to regulate meristem activities.
Recently, a YAB homologue gene SH1 and its homologue genes were identified to regulate seed shattering in cereal species, including sorghum, rice and maize [ 20].
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