Over forty such alleles have been identified by sequencing the KIT genes of various horses.
While the total depth of sequencing required may be calculated theoretically based on degree of enrichment [12], determining the degree to which highly enriched regions identified by the microarray have been identified by sequencing reads may provide an empirical check that adequate sequencing depth has been reached.
Around 539 wheat miRNAs putatively associated with development and stress response have been identified by sequencing small RNA population [ 24, 30- 36] (Additional file 1: Table S1).
Melanoma is the most deadly form of skin cancer, and we showed that activation of a mutant BRAF, carrying a mutation that had been identified by sequencing in human melanoma, was one of the primary events in melanoma development.
So far, an intact and potentially functional mitochondrial copy of rps14 has been identified by sequencing in relatively few plants, namely, Oenothera [ 21], Brassica [ 22, 23], pea [ 24], and broad bean [ 25].
Because not all mutations in p53 lead to IHC evidence of p53 over-expression, we assessed the sensitivity and specificity of IHC for detecting p53 mutations that had been identified by sequencing.
