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Traditionally, novel compounds with antiprotozoan activities have been identified by screening of compound libraries in high-throughput systems.
Although mutations associated with autism have been identified by screening as few as several hundred patients [32], [33], one limitation of our study is the relatively small number of patients screened for rare variants.
In Arabidopsis, several genes involved in the formation of the secondary wall have been identified by screening for irregular xylem (irx) mutants and analysis of genes co-expressed with genes already shown to be involved in secondary wall formation [11], [12].
Using a fluorescent binding assay, several small molecule inhibitors of MurG have been identified by screening of combinatorial libraries.
Potential targets of such protective immunity have been identified by screening crude antigen preparations and expression libraries with sera from animals vaccinated with irradiated L3s [ 11, 12].
Starting points for these efforts have been identified by screening of compound collections, either in phenotypic cell-based assays or in biochemical target-based assays.
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A fourth hit, 9-methoxy-camptothecin, was identified by screening the natural compound library in the absence of verapamil.
The MAT1-2 gene was identified by screening a genomic library from the MAT1-2 IPO94269IPO94269 with a heterologous probe from Tapesia yallundae.
The metabolically most active clones were identified by screening for high specific glucose uptake rates during ammonium starvation-induced stationary phase in deep-well microtiter plates.
The sequence was identified by screening a phage display library against a DC cell line (JAWSII) using mouse TNFα as the eluting ligand.
4- 1-Phenyl-1H-pyrazol-4-yl 4- 1-Phenyl-1H-pyrazol-4-yl 4- 1-Phenyl-1H-pyrazol-4-yl 4- 1-Phenyl-1H-pyrazol-4-yl 4- 1-Phenyl-1H-pyrazol-4-yl 4- 1-Phenyl-1H-pyrazol-4-yl 4- 1-Phenyl-1H-pyrazol-4-yl
More suggestions(16)
been identified by monitor
been identified by selection
been identified by inspection
been prevented by screening
been selected by screening
been diagnosed by screening
been investigated by screening
been cloned by screening
been defined by screening
been obtained by screening
been reduced by screening
been developed by screening
been demonstrated by screening
been advanced by screening
been minimised by screening
been performed by screening
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com