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To date, many lepr genes has been identified and functionally characterized in vertebrates, however relatively few molecular or functional studies of invertebrate lepr genes have been conducted.
Many participants during these steps have been identified and functionally validated.
Although various OCTN carnitine transporters have been identified and functionally characterized, their membrane localization and regulation are still unknown and must be investigated.
Because most of the structural genes of glucosinolate metabolism have been identified and functionally characterized in Arabidopsis thaliana, current research increasingly focuses on questions related to the regulation of glucosinolate synthesis, distribution and degradation as well as to the feasibility of engineering customized glucosinolate profiles.
In vertebrates, a rapidly increasing number of long non-coding RNAs (lncRNAs >200 bp) have been identified and functionally annotated (Guttman et al., 2009; Guttman and Rinn, 2012; Huarte and Rinn, 2010; Rinn et al., 2011), among which some are regulated by p53.
Unfortunately, except for the literature on the genetic basis of reproductive senescence in human males [e.g., 51], relatively few genes and proteins that underlie male reproductive senescence have been identified and functionally evaluated.
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Six CYP93E orthologs, exclusively from leguminous plant species, were identified and functionally characterized in S. cerevisiae.
Up to nine tissue- or development-specific VGSC subtypes (Nav1.1-1.9 Nav1.1-1.9tified and functionally characterized.
Overexpression of Abcg2 efflux transporter was identified and functionally validated as the predominant mechanism of acquired Danusertib resistance in vitro.
Finally, candidate genes were identified and functionally tested.
To study kiwifruit flower development, nine MADS-box genes were identified and functionally characterized.
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