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Several mechanisms have been hypothesized to link CMV infection and CVD in both human and animal studies [15] [20].
Thus, many characteristics that have been hypothesized to link sipunculans with molluscs, including their developmental pattern and lack of segmentation, should be reevaluated.
Epigenetic mechanisms have also been hypothesized to link birth weight, a proxy for the well-being of the offspring in utero, with some of these cancers in adulthood [ 9– 15].
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Thus, low vitamin D is hypothesized to link with mortality in this setting.
While the deficient executive pathway is assumed to involve an insufficient regulation of thought and action primarily characterized by a core deficit in inhibitory control, the dysfunctional motivational pathway is hypothesized to link behavioral symptoms, task engagement, and a biologically embedded alteration in reinforcement mechanisms.
The higher than average severity in 1999 has been hypothesized to be linked to the particularly severe 1997 1998 influenza seasons in the swine population [35].
Teriflunomide is highly protein-bound and free concentrations have been hypothesized to be linked to response.
The re-emergence of serogroup A in the late 1990s has been hypothesized to be linked to immigrants moving to Greece from Eastern European countries, where serogroup A is known to be prevalent [ 36].
Androgens have been hypothesized to be linked to neuropsychiatric conditions that asymmetrically affect the sexes (e.g., conduct disorder, psychopathy, attention-deficit/hyperactivity disorder, substance abuse, depression, bipolar disorder, cluster B personality disorders, intermittent explosive disorder, autism) (1 11,14,18,58 63).
PPAR γ has been hypothesized to provide a metabolic link between obesity and tissue dysfunction.
The increased conversion of androgens to estrogens by the aromatase enzyme in peripheral adipose tissues [ 4] along with reduced levels of serum sex hormone binding globulin have been hypothesized to be the main link between obesity and increased risk of postmenopausal breast cancer [ 2].
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