Sentence examples for been hypothesized to inhibit from inspiring English sources
These high levels of catecholamines have also been hypothesized to inhibit insulin secretion and to activate lipolysis of adipose tissue resulting in increased plasma FFA [ 12, 13].
The induction of SOCS proteins by hormones and/or cytokines has been hypothesized to inhibit GH signaling by a negative feedback loop involving the janus kinase and signal transducer and activator pathway [ 12].
ROS have been hypothesized to inhibit the cell signaling of the insulin receptor by blocking the pathway between insulin-receptor substrate 1 (IRS-1) and phosphatidylinositol-4,5-bisphosphate 3-kinase, thereby inducing insulin resistance (IR) [ 17].
Thus, disruption of functional survivin along its dimer interface with a small molecule is hypothesized to inhibit the proliferation of cancer cells and sensitize them to therapeutic agents and radiation.
Intense mitochondrial fluorescence was anticipated, as this drug is hypothesized to inhibit the PTP and possibly the subsequent MPT.
UVR promotes vitamin D synthesis and vitamin D is demonstrated to regulate several genes involved in cancer processes and is hypothesized to inhibit cancer development [ 38].
For example, TRPA1, TRPM8, TRPV1, and TRPV3 are key channels that transmit the itch sensation [ 44]; the TRPV1 and TRPV3 play an important role in histamine dependent itch transduction, but the TRPM8 ion channel is hypothesized to inhibit itch signal transmission [ 27].
Interestingly, during glycogenolysis, exposure of the glycogen branches has been hypothesized to directly inhibit AMPK [ 49].
Diets that are high in fiber have been hypothesized to protect against breast cancer by inhibiting the intestinal reabsorption of biliary excreted estrogens.
These compounds were initially hypothesized to inhibit the enzymes through the previously described nucleophilic attack/elimination/Lössen rearrangement reported by Groutas et al. for the structurally similar succinamide inhibitors of elastase.
Obese glucose-tolerant subjects are hypothesized to exhibit tonically inhibited serum CBG levels.
