Sentence examples for been hypothesized that selective from inspiring English sources

It has been hypothesized that selective sweeps (positive selection) and negative selection influence the evolution of the Y chromosome, which may explain its relatively low genetic variability [22].

It has been hypothesized that selective COX-2 inhibition upsets the thrombotic equilibrium and creates an imbalance between anti-thrombotic and pro-thrombotic factors by blocking endothelium-derived prostaglandin (PG) I2 while sparing platelet-derived thromboxane [ 5, 6].

Given South Africa's high incidence of tuberculosis and subsequent widespread use of rifampicin, it has been hypothesized that selective pressure has resulted in the emergence of rifampicin resistant MRSA.

It has been hypothesized that selective inhibition of COX-2 may alter the balance between the antithrombotic prostacyclin and prothrombotic TXA2, selectively inhibiting the production of prostacyclin and allowing the effects of thromboxane to predominate, thereby promoting a prothrombotic state (Jones 2005).

Therefore, it was hypothesized that: H1.

It has also been hypothesized that a selective inhibitor of LYP could revert the negative effects of the R620W variant on TCR and BCR signaling, and thus might constitute an effective targeted therapy for autoimmunity in carriers of the autoimmune-predisposing variant [ 3].

It has been hypothesized that organisms would derive a selective advantage by optimizing the organization of their sensory and neural information processing according to suitable informational criteria [22] [25].

Biofilm formation (as studied in the laboratory environment) positively selects for cells in an agn43 ON state, and it has been hypothesized that during host colonization the same selective pressure for agn43 ON cells will also exist (Chauhan et al. 2013).

It has therefore long been hypothesized that it should be possible to design selective GC receptor agonists, with preserved transrepression actions and reduced transactivation effects, allowing the preservation of beneficial effects while reducing side effects [ 5, 6].

Therefore, it has been hypothesized that other mechanisms, such as a past selective event or random genetic drift, would explain for the high frequency of CF in European populations.

As already discussed, it has been hypothesized that iron limitation might have been one of the selective forces in evolution of cyanobacteria.