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It has been hypothesised that increases in fecundity might entail an increased mutation rate [ 46], or reflect increased variance in offspring viability, and so lower effective population size [ 79].
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It has been hypothesised that increased pain in the postoperative period, and depression may be predictors of the development of postoperative stiff shoulder.
The animal health benefits of increased lactation persistency are speculative at present; but it has been hypothesised that increased lactation persistency is associated with lower incidences of peri-parturient metabolic diseases [ 4].
It has been hypothesised that increased glucose uptake may represent an important regulatory point in maintaining the growth and synthetic activity of malignant cells and suppression of apoptosis (Greiner et al, 1994; Kan et al, 1994).
It has also been hypothesised that increased local expression of pro-inflammatory cytokines observed in the external intercostal muscles of patients with COPD may contribute to respiratory muscle dysfunction [ 33], potentially having a progressively detrimental impact as ventilatory demands increase, such as during a COPD exacerbation.
As it was hypothesised that increases in goal specificity would be part of a broader shift in processing style in individuals receiving MBCT, we also examined whether changes in goal specificity were associated with comparable changes in autobiographical memory specificity, and whether changes in mood mediated the effects of treatment on goal-related processing.
It was hypothesised that increased levels of arabinofuranosidase, β-galactosidase, endo-arabinanase, endo-galactanase, exo-polygalacturonase, pectin de-esterifying enzymes and endo-polygalacturonase contributed to a synergy in degrading pectin in CRP from 12 to 24 h of fermentation.
Consequently, it could be hypothesised that increased arterial stiffness, as assessed by PWV, provides a plausible link between the development of PE in the index pregnancy and the increased propensity to cardiovascular events that these women experience later on in life [27].
It could be hypothesised that increased serum folate results in an increase in the reduced folate pool and hence increased TS inhibition, increased drug activity and, therefore, increased toxicity.
Given the frequently observed coexpression of TATI and trypsin in cancer, it can be hypothesised that increased levels of TATI reflect a simultaneous elevation of trypsin and, hence, increased propensity of the tumour cells to invade and spread.
Based on analyses using dynamic magnetic resonance imaging [ 21], it could be hypothesised that increased peak hip adduction, hip internal rotation and contralateral pelvic drop during running would result in focal retropatellar overload.
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