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It has been hypothesised that an increased dosage of Kcnj6 together with Dyrk1a might explain the synaptic phenotype of Ts1Rhr mice (Belichenko et al., 2009).
It has been hypothesised that an age-associated decrease in DNA repair contributes to the development of HCC (Goukassian et al, 2000; Anisimov, 2007).
Consequently, it has been hypothesised that an inhibitor of VEGF signalling would be particularly efficacious in inhibiting tumour growth in the patients that overexpress VEGF (Mendel et al, 2000).
Recently, it has been hypothesised that an alternative receptor for rHuEpo, a heterodimer of EpoR and the β-common chain, mediates tissue-protective effects in non-haematopoietic tissues (Brines et al, 2004).
For example, it has been hypothesised that an anteriorly placed artery stiffened by atherosclerosis compresses the underlying vein against the neural retina, reducing blood flow downstream of the crossing.
It has been hypothesised that an upregulation of the neuropeptide substance P (SP) and its preferred receptor, the neurokinin-1 receptor (NK-1 R), is a causative factor in inducing tenocyte hypercellularity, a characteristic of tendinosis, through both proliferative and antiapoptotic stimuli.
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As the stiffness of a wire is inversely proportional to its length [8 10], it has been hypothesised that a straight lingual archwire, being shorter than the corresponding mushroom archwire, should aid the clinician in keeping bowing effect under control [11 13].
It has been hypothesised that a Proto-Indo-European word morwi- was used, cf. Sanskrit vamrah, Latin formīca, Greek μύρμηξ mýrmēx, Old Church Slavonic mraviji, Old Irish moirb, Old Norse maurr, Dutch mier.
It has also been hypothesised that a mucinous pathway of carcinogenesis leads to a mucinous phenotype (Hanski, 1995).
It has been hypothesised that a decision about treatment is influenced by how 'easily' the farmer can initiate individual treatments.
It has been hypothesised that a multigenic model might explain breast cancer susceptibility in a large part of the population.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com