However, reliance on data from routine surveillance to estimate age-specific attack rates during an emerging pandemic is hampered by changes in the sensitivity and specificity of clinical surveillance schemes and the proportion of subclinical infections [10], [11].
Comparability among indirect causes was hampered by changes in the data collection forms.
The current study was hampered by changes in research governance procedures, 13 14 which made it difficult to trace the children because of concerns about privacy and restrictions on NHS trusts over access for employees of other organisations to carry out research evaluations.
The demonstration of in vivo consequences of chemokine/GAG interactions have been hampered by conformational changes consecutive to the mutagenesis of BBXB consensus sites that leads frequently to an overall reduced affinity of the chemokine for the corresponding receptor [22].
Attempts to trace the genealogy of the Uralic languages to periods earlier than Proto-Uralic have been hampered by the great changes in the attested languages, which preserve relatively few features and therefore provide little evidence upon which scholars may base meaningful claims for a more distant relationship.
"However, previous reforms have often been hampered by continuous revolution and change, rather than allowing policies time to take hold," Marcus Mason, the BCC's head of education and skills, said.
Under Mr. Cox, the enforcement division has been hampered by budget cuts and rule changes that have made it more difficult to impose penalties on companies found guilty of wrongdoing.
Although cytogenetic studies on CC have identified a number of non-random karyotypic changes involving chromosomes 1, 3, 5, 17, and X [ 4], the search for the critical cytogenetic changes has been hampered by technical difficulties in culturing tumor cells and inherent karyotypic complexity in this tumor.
A full assessment of tectonic movement, sea-level oscillation, deposition of alluvium, river shifts, and long-term patterns of climatic change has been hampered by a lack of data from Iraq, although important information on some of those processes has been obtained by studying the Persian Gulf.
Research into novel therapies for acute kidney injury (AKI) has been hampered by reliance on a diagnosis predicated on changes in serum creatinine level.
