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Indeed, over 20 different rodent models of this disease have been generated to date (for the review see [ 15]).
Elovl3-, Elovl5-, Elovl6-null Elovl6-null mice, 38 and mutant Elov4 knock-in mice have been generated to date (November 2010).
Before elaborating on the Brca1 conventional and conditional mouse models that have been generated to date, we will discuss the characteristics of human BRCA1-related breast cancer in more detail.
Of the knockouts on this pathway that have been generated to date, the only ones that survive birth are the TGF-β1-null and the Smad3-null mice [ 19, 20, 21, 22, 23].
However, pathogenetic mechanisms of neoplastic transformation are still unclear; several growth factors and tumour suppressor genes (Collier et al, 1993; Naka et al, 1998; Abou-Shady et al, 1999) have been involved but insufficient data have been generated to date.
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Offerpal isn't saying what the size of the transaction is, or how much revenue Tapjoy is generating to date.
To date no study has been generated to look into hemoptysis patterns, in this nation.
Some measures have been developed for community engagement broadly, and for community-based participatory research in particular, though they are few and the evidence generated to date is thin [ 41, 42].
In the absence of experimental or human evidence that vaccination (either the MMR vaccine or the preservative thimerosal) affects metabolic, developmental, immune, or other physiological or molecular mechanisms that are causally related to the development of autism, the committee concludes that the hypotheses generated to date are theoretical only".
EST data generated to date are clearly insufficient to describe in greater detail transcriptional activities of HML-2 and other HERVs in human tissues and cell types.
The total number of enhancer trap lines generated to date is: 24 CK (Et(cfos KalTA4)), 25 NRCK (Et(2xNRSE-cfos:KalTA4)) 2xNRSE-cfos KalTA4Et(2xNRSE-cfos:KalTA4, 2xNRSE-cfos KalTA4P)), andwell as 37 CK-5xN-14xY (Et(26NRCK-5xMY:KalTA4, 5xUAS-Etb:nfsB, 2xNRSE-cfos KalTA4). 2xNRSE-cfos KalTA4
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been performed to date
been considered to date
been described to date
been presented to date
been filed to date
been excavated to date
been done to date
been pledged to date
been published to date
been undertaken to date
been arrested to date
been developed to date
been fudged to date
been elucidated to date
been wounded to date
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