Sentence examples for been generated and have from inspiring English sources
Murine IBD models, which are genetically engineered to lack some susceptibility genes, have been generated, and have provided useful insights into the therapeutic potential of targeting the susceptibility genes directly or their downstream pathways indirectly for IBD.
Cardiomyocyte-specific CYP2J2 transgenic (Tr) mice have been generated and have a normal heart anatomy and contractile function [15].
Two models, one donor (GT) and one acceptor (AG) model have been generated and have been used for EuGène training.
Null mutations of the latter gene have been generated and have a developmental defect in skin formation similar to that we observed [ 15].
E- selectin knockout mice have also been generated and have defects in neutrophil infiltration in different tissues that are exacerbated when combined with P- selectin knockout mice [ 51], but in an EAE model deficiency in E- selectin does not affect the progression of the disease [ 50].
A monoclonal antibody recognizing mouse gp75/TRP-1 has been generated and has shown activity in mice when infused either as single agent or in combination with vaccines eliciting CD8+ T cell responses [13], [14].
Ten replicates of a representative scenario used to study genomic selection in livestock were generated and have been made publically available.
To investigate the role of RTKs in mammary tumorigenesis, transgenic mice bearing the wild-type (wt) or mutated, activated rat c- neu (ErbB2) were generated, and have been widely studied [ 28- 31].
To minimise systematic biases, stock plates were generated and have been used to generate plates of DNA for genotyping, which contain a mixture of cases and controls along with the negative and positive controls (an empty well and a sample with known genotype) designed to address genotyping quality control, plate identification and orientation.
However, how the PEDV variant was generated and has evolved is not clear.
It is perhaps noteworthy that those animals that are less unambiguous are those for which fewer reads were generated and had lower levels of coverage across genes.
