Sentence examples for been functionally validated in from inspiring English sources

Only a few genes involved in the DNA repair process have been characterised and their functions have been functionally validated in monocot crops, including rice [ 14].

Only a limited number of MADS genes have been functionally validated in rice.

In spite of this, only a small part of bZIP transcription factors have been functionally validated in plants.

Among the different types of Zn finger families, role of C2H2 type Zn finger gene families in drought stress tolerance has been functionally validated in rice and Arabidopsis [ 64, 65].

Five of these have been functionally validated in previous studies; miR-19a targeting CCND1, miR-125b targeting ERBB3, miR-141 targeting YAP1, miR-222 targeting BCL2L11 and miR-497 targeting MAP2K1 (Additional file 4M).

In addition to some of the well characterized genes described above, there are several others, e.g. OsMADS34, 32, 20, 72, 63, 98, 89, 92 and 86, that show specific up-regulation in panicles but have not yet been functionally validated in rice.

Furthermore, the clinical associations we observed with SLCO1B1 were functionally validated in vitro.

A number of the microRNA-protein associations were functionally validated in a breast cancer cell line.

Finally, ABCC5 was functionally validated in in vivo models to be an important mediator in breast cancer outgrowth in this organ.

Furthermore, a subset of the estimated miRNA-protein associations was functionally validated in the MDA-MB-231 cell line, including four associations that were in silico predicted.

We found that 90 of 178 (50.6%) biological contexts predicted to be enriched with TF+TG+ activity were functionally validated in previous experiments (see Section 2).