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Its roles have been ascertained for homeostasis of liver and pancreatic function and have been functionally linked to diabetes [25].
A number of mutations in PFN1 have been functionally linked to neurodegeneration in fALS1,2,5, but the mechanism of PFN1 neurotoxicity remains undetermined.
These findings suggest that relatively large jaw-muscle PCSAs can be added to the suite of masticatory features that have been functionally linked to the exploitation of a more resistant diet by C. apella.
Regulated in development and DNA damage response 1 (REDD1) has been functionally linked to the control of diverse cellular processes due, at least in part, to its ability to repress mammalian or mechanistic Target of Rapamycin (mTOR) Complex-1 (mTORC1), a key protein complex controlled by hormonal and nutrient cues.
The precuneus/PCC, which is the strongest hub in the brain has been functionally linked to regions that constitute the DMN and plays a pivotal role in the DMN [15, 26].
However, thalamus activity was frequently observed during perception and cognition and has been functionally linked to attention [58], [59], [60], specifically the alerting component [61].
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To test whether the ability of Xrn1 to interact with eIF4G is functionally linked to its role in translation we designed a gain-of-function experiment.
Cossec, J. C. et al. Trisomy for synaptojanin1 in Down syndrome is functionally linked to the enlargement of early endosomes.
Wei, C. et al. Repression of the central splicing regulator RBFox2 is functionally linked to pressure overload-induced heart failure.
Mal, A. & Harter, M. L. MyoD is functionally linked to the silencing of a muscle-specific regulatory gene prior to skeletal myogenesis.
Evidence suggests that patterns of benthic community structure are functionally linked to estuarine processes and physical characteristics of the benthos.
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