Sentence examples for been functionally demonstrated to from inspiring English sources

The target gene selection was augmented by parsing the literature for candidate factors, i.e. yeast and mammalian proteins that have been functionally demonstrated to be involved in trafficking.

As expected, many processes that were enriched have been functionally demonstrated to be controlled by PPARα, including cellular ketone metabolic process, lipid metabolic process, cellular amino acid and derivative metabolic process, peroxisome organization, and mitochondrion organization.

The groups with the cycles were functionally demonstrated to transport oligopeptides and the groups with the triangles were experimentally demonstrated to transport metal compounds.

The previously published Y356C and R826W mutations (4, 6, 7, 13) were functionally demonstrated to alter MgATP sensitivity or ATPase activity of SUR1, respectively, leading to KATP channel activation with increased resting whole-cell currents (7, 13).

(The term ICR is more properly reserved for those gDMRs that have been functionally demonstrated, either through targeted mutagenesis in the mouse or the occurrence of mutations in imprinted gene syndromes, to control imprinted expression in cis of several genes in a cluster).

If overexpression has been functionally demonstrated in ventricular myocytes from failing human hearts.

The crucial role played by Wnt signalling during segment addition has been functionally demonstrated in a few arthropods.

This is illustrated by the case of CYP6CM1 whose implication in neonicotinoid resistance has been functionally demonstrated; although in the present study, no significant correlation was found.

Luminal/brush border type I and II AII receptors have been functionally demonstrated in intestine where luminal AII, through the type I receptor, inhibits apical Na+-dependent glucose transport [ 33].

This is the first single biomarker that has been demonstrated to be functionally involved in stem cell maintenance.

Both R1 and B1 are basic helix loop helix transcription factors that have been demonstrated to be functionally redundant in maize.