Importantly, many genes have been functionally assigned to hormone activity, including two GnRH forms (salmon GnRH and chicken GnRH-II), growth hormone (GH), isotocin, LH, tachykinin, neuropeptide Y (NPY), pituitary adenlyate cyclase activating polypeptide 1 beta (PACAP 1β).
Our results revealed that deletions of functionally related genes caused similar morphologic phenotypes, enabling loci to be functionally assigned to a specific cellular pathway [8].
The majority of these genes were functionally assigned to cell cycle, DNA replication and repair and purine and pyrimidine metabolism; 63% of the encoded proteins were nuclear (Figure S5).
Two of the subclades were functionally assigned to the biosynthesis of furanocoumarins.
Totally 14,105 sequences were identified with pathway annotation, and they were functionally assigned to 125 KEGG pathways.
Forty-four of these loci (32%) were functionally assigned to the photosynthetic light harvesting process, electron transport or RuBisCO activase.
The IZH family of genes has pleiotropic effects on gene expression and their cellular roles cannot yet be functionally assigned to a single biochemical pathway [ 18, 19].
We found that 776 (31%) of 2258 rESTs could be functionally assigned to biological processes (n = 540), cellular components (n = 328) and molecular functions (n = 457).
Analyzing RIP-Chip data by Ingenuity software revealed that among these HuR-enriched mRNAs 49 mRNA species can be functionally assigned to cell death and survival (marked rows of Supplementary Table).
We found that of the 1,185 DEGs, 28% (n = 334) could be functionally assigned to biological processes (n = 548), cellular components (n = 417) and molecular functions (n = 537) with total of 1,141 GO terms.
However, the synteny between both genomes is interrupted due to the presence of additional genes in the C. variabile chromosome that were functionally assigned to a phage island, several transposon hotspots, and species-specific gene islands, the latter containing for instance large gene clusters involved in iron acquisition and siderophore biosynthesis.
