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In P. berghei, the ApiAP2 transcriptional regulators AP2-O and AP2-Sp have been functionally analyzed in the nonerythrocytic ookinete and sporozoite life stages, respectively, and were found to serve as master regulators of parasite development in the mosquito (Yuda et al., 2010; Yuda et al., 2009).
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Then, all the nominal groups were functionally analyzed in terms of both post-modifiers, including Prepositional Group, To-infinitive Clause, Past Participle and Present Participle, pre-modifiers.
These candidate variants underwent selection based on in silico predictions for regulatory potential and disruption of transcription factor binding, and were functionally analyzed in vitro and in vivo in normal and breast cancer cell lines.
Genes which are differentially associated with H2A.Z in LD611 cancer cells were functionally analyzed in the context of gene ontology and molecular networks by using Ingenuity pathway software (IPA; http://www.ingenuity.com).com
NF-kB binding sites mediating TNFα responses through the canonical pathway are present in all three promoters but have not yet been functionally analyzed.
Nine genes have been reported to exhibit expression in the developing nervous system (her3: [4]; her4: [8]; her5: [9]; her6: [10]; her9: [11]; her11: [7]; her12 and her15:[7]; hey2: [12]) and six (her3, her4, her5, her6, her9, her11) have been functionally analyzed.
In silico analyses detected putative SBE sites also in the promoter regions of the LAMB3 and the LAMC2 genes but have not yet been functionally analyzed.
Surprisingly, SElW has not yet been functionally analyzed, despite extensive study of staphylococcal SAgs.
All unigenes obtained were functionally analyzed via the Sequence Analysis and Management System (SAMS).
Therefore, it is premature to associate allele changes with a phenotype, disease severity, or events of epidemiologic importance until they are functionally analyzed individually and cumulatively in a model system.
Other promoters for sHSP genes expressed in plant seeds are yet to be functionally analyzed.
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