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In retrospect, the optimal dosing protocol for ixabepilone had not yet been fully established at the time of this trial design.
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This increase can only be partly explained by an activation of alternative pathways since the re-activation of the MAPK pathway seems to be fully established at day 3 that is 2 days later than the up-regulation of cyclin D1 could be observed.
In February 1945, No. 34 Squadron commenced a relocation to Morotai in the Dutch East Indies, under the control of the Australian First Tactical Air Force, and was fully established at its new base by mid-April.
However, once amastigote infection is fully established at 48 h, surface HASPB is only weakly detectable (Fig. 6A bottom panel).
But by 1936 she was fully established as the Führer's companion.
At the time of writing this paper (2016), it is clear that BREXIT is fully established as a lexeme as we will see below.
However, the amount of protective antibody needed at mucosal surfaces has not been fully established.
The cause of the calamity has never been fully established despite a 10-year investigation.
However, the relationship of viability to long-term mortality has not been fully established.
Whether he carried a gun has not been fully established.
Additionally, TIGTA said "timeliness standards for processing claims have not been fully established".
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