Sentence examples for been fully elucidated however from inspiring English sources

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The mechanism underlying desensitization has not yet been fully elucidated, however, it appears to be calcium dependent [25], [26], [40].

Furthermore, the effector responses of chicken T cells against AIV have not been fully elucidated, however, it has recently been shown that AIV infection induces up-regulation of cytokines such as IFN-γ [17].

In the case of ALECT2, the exact mechanism of disease has not been fully elucidated; however, a genetic component is suspected [ 1].

The catabolic pathway for the major isomers other than γ-HCH has not been fully elucidated; however, lin genes are known to play a role.

The mechanism by which this occurs has not been fully elucidated; however, there is some suggestion that it is pertussis toxin-sensitive Gαi coupling (Schepp et al., 1992).

This class has not yet been fully elucidated; however, solvation and net charges on the protein are postulated to play a role in this class of proteins.

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The MNV signal thus exhibits many of the features and functional characteristics of the stop-start signals of FCV, RHDV and influenza B. The molecular mechanism of termination-reinitiation remains to be fully elucidated, however.

The phenotype of Breg cells in humans has yet to be fully elucidated; however, human B cells capable of suppressing T cell responses have been described.

The underlying mechanism of pathway inhibition remains to be fully elucidated; however, it may depend on the palmitoylation of Wnt, a modification requisite for the activity of this protein (Clevers and Nusse, 2012, Fiorentino et al., 2008).

29 The downstream signaling of GPR55 remains to be fully elucidated; however, it is known to use Gα13 for signal transduction and to activate PLC, RhoA, ROCK, ERK, p38 mitogen activated protein kinase, and Ca2+ release that can induce downstream transcription factors such as NFAT, NF-κB, CREB, and ATF2.

The mechanism by which Rheb-GTP activates mTORC1 has not been fully elucidated yet, however it requires Rheb farnesylation and can be blocked by farnesyl transferase (FT) inhibitors.It has been proposed that Rheb-GTP would relieve the inhibitory function of FKBP38 (another component of mTORC1) on mTOR, thus leading to mTORC1 activation [ 44].

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