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One glucose transporter (GLUT5) isoform has been found to functionally serve as a high-affinity fructose transporter [22].
Some proteins that participate in the recombinational repair pathway have been found to functionally interact with WRN.
Consistent with this, LmjF32.2740 (LmACR2) has been found to functionally complement the arsenate-sensitive phenotype of the ScACR2 deletion in S. cerevisiae.
This domain is not conserved among other steroid receptors, but ER has been found to functionally interact with c-Src via MNAR (1, 26), and the transactivation activity of GR has been reported to be opposed by MNAR expression (5).
Both RBf1 and RBf2 mediate transcriptional repression; however, these proteins have different inherent ability to interact with E2F proteins; RBf1 has been found to functionally interact with both the activator dE2F1 as well as the repressor dE2F2, whereas RBf2 is found to interact with dE2F2 but not dE2F1 (Frolov et al. 2001; Stevaux et al. 2002).
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Using a Nanog-Luciferase reporter as readout, Kenpaullone was found to functionally replace Klf4 in the presence of OSM (Lyssiotis et al., 2009).
A similar number have been found to be "functionally obsolete".
In hydrogeological investigations, transverse resistance (R) has been found to be functionally analogous to transmissivity ((T)) (Cassiani and Medina 1997; Niwas and Singhal 1985).
Genes involved in muscle growth, muscle contraction and specific metabolic pathways have been found to be functionally relevant for the early performance evaluation of elite athletic horses.
Slug and Snail have been found to be functionally similar, but not identical.
In fact, clusters identified by GCM but not by GLM have been found to be functionally relevant [16].
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