To add additional confusion to the issue of pathogenicity, more than one HLA allele has been found to associate with disease, for example DR3 and DR2, and these associations are not necessarily confined to a single ethnic group [ 37].
Many cancers have been found to associate with inflammation as exemplified by the infiltration of tumour-associated macrophages and regulator T cells, and inflammation can further aggravate cancer progression (Grivennikov et al, 2010).
Intrinsic features of the TILs infused, such as the number of tumor reactive T cells, their differentiation status as well as their persistence in circulation, have been found to associate with clinical benefit from ACT2, 3, 5, 6.
These polyphenols have been found to associate with several health benefits [15].
The well-known oncogenic viruses Epstein-Barr Virus (EBV) has also been found to associate with enhanced EMT markers in HNC lesions [64] (Table 1).
In contrast to our findings, AKI has been found to associate with increased 1-year mortality among 30-day ICU survivors in a retrospective database analysis [5].
This variant has previously been found to associate with obesity on its own [8], [9].
To date, very few proteins have been found to associate with Plk4.
Importantly Tks5 has also been found to associate with ADAMs family proteases and to localise to podosomes in response to Src activation [21], [41].
With regard to VEGF and cervical cancer, a high pretreatment level has been found to associate with large tumors, stromal invasion and pelvic lymph node metastasis.
In mammalian cells, ASAPs have been found to associate with focal adhesions, invadopodia, and circular dorsal ruffles where they regulate the structures and the associated actin cytoskeleton [9].
