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Different marker percentages have also been found in colon and liver cancer cells [30], [31], [32].
Rare mutations in Axin have also been found in colon tumours.
Loss of function mutations in PPARs that impaired ligand binding have also been found in colon cancer [ 13].
For example, loss of hetero-zygosity for Klf4 and Klf5 has been found in colon, stomach, breast, prostate and liver cancers [ 90, 91].
Besides mutations in APC, inactivating mutations in Axin2 as well as gain-of-function mutations in β-catenin have also been found in colon cancer patients, albeit with relatively low frequency [ 148– 148].
The liver is the main source of both MASP-1 and MASP-2, but low expression at the mRNA level has also been found in colon, heart, lung, kidney, placenta, brain (for MASP-1), and in testis and small intestine (for both MASP-1 and MASP-2) [ 20].
Similar(54)
The syndrome, Dr. Feinberg and Dr. DeBaun found, was often caused by changes in the expression of a cluster of genes, and those changes also are found in colon and lung cancers.
Amongst others reduced cellular infiltration and myeloperoxidase activity were found in colon and within lesions lower IFNγ and IL-18 production was detected [50].
Highest levels of CDCP1 expression are found in colon, skin, small intestine, and prostate [ 14- 16].
Cancers showing mutations in p53 are found in colon, lung, esophagus, breast, liver, brain, reticuloendothelial tissues and hemopoietic tissues [ 100].
High concentrations of PG are found in colon tumors and in blood of patients with colorectal cancer.
More suggestions(15)
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