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But since then cancer stem cells have been found in brain, colon, head and neck, pancreatic and skin tumors.
The relationship between exposure to 50-Hz magnetic fields and human health is of increasing interest since associations have been found in brain cancer in adults and childhood leukemia.
CD90, another most important surface marker of CSCs, has been found in brain, breast, lung, liver, pancreatic, and esophageal cancer types (Woo et al., 2015; Wang et al., 2015; Khan and Mukhtar, 2015; Sukowati et al., 2013; Zhu et al., 2014; Tang et al., 2013).
You've noted that the abnormalities have been found in brain stem systems and the cerebellum in the early fetal stage -- before the cerebral neocortex is functional.
Nitrated alpha synuclein and tau have been found in brain of patients with Parkinson's and Alzheimer's diseases [51], [52].
Upregulated SOX11 has been found in brain tumors and in ovarian carcinoma, where it has been associated to tumorigenesis and clinical outcome [13], [14], [15], [16], [17].
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In the last decade a brain constituent, S100B protein, has been proposed as a consolidated marker of brain damage [3], since elevated S100B concentrations in biological fluids have been found in brain-damaged adults, infants and fetuses [3] [12].
Interestingly, neurofibrillary tangles have been found in brains of chronic alcoholics possessing neuropathological signs of thiamine-deficiency [40], [47].
Tau protein hyperphosphorylation has been found in brains of both humans with HAND, and the murine model, to be associated with neuronal damage and loss.
Interestingly, increased IL-1 expression has been found in brains of individuals with Down syndrome and Alzheimer's disease [ 46].
Furthermore, NF-κB activity has been found in brains of scrapie-infected mice at the terminal state of the disease (Kim et al., 1999).
More suggestions(15)
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com