No group differences in adverse event rates were found and no clinically relevant differences in blood safety parameters were noted.
In our study, no significant differences in mean arterial pressure between the two groups were found and, therefore, clinically relevant changes in splanchnic vascular resistance after TELM administration are unlikely.
A summary of the percentage of anti-Ku-positive patients, as determined by CIE/LIA to all autoantibodies measured in this study, is shown in Figure 2. A single anti-Ku positive (positive for both anti-Ku p70 and anti-Ku p80 antibodies) anti-centromere antibodies (ACA -positive cACA -positive, and this patient was caseically diagnosed as having SLE/Sjögren syndrome.
They have been found clinically and statistically effective in improving disease parameters and quality of life of patients and reducing mortality.
Early diagnosis and treatment of glaucoma has been found clinically beneficial and cost effective as it significantly delays visual field deterioration (4, 5).
Mutations in GRN and MAPT, two genes associated with frontotemporal dementia (FTD), have been found in clinically diagnosed AD cases.
Despite advances in high throughput proteomic characterization of aberrant protein expression and disease-specific differentiation from normal colonic tissue, very few biomarkers have been found to be clinically useful and have attained widespread clinical application [ 23, 24].
This clade 1 isolate bears a PQRERRKKR/GLF motif at the HA0 cleavage site, and has an intravenous pathogenicity index (IVPI) of 2.9 in specific pathogen free (SPF) chickens; in addition, it has been found to induce clinically overt and lethal neurological disease in adult Pekin ducks (Harder et al., unpublished).
A minimum change of 5%to10%0% has been found to be clinically significant for symptom and quality-of-life analyses [ 31].
Furthermore, it has been found to be clinically relevant, easily administered, valid, and a reliable measure of preferred roles in health care decision making [ 40, 41].
