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To date, most vaginal microbicides under clinical investigation have been formulated as single-dose semi-solid gels, designed for application to the vagina before each act of intercourse.
Although both methods are formulated as single QTL models, they are often applied for constructing scan statistics to decide whether a QTL exists at a particular location, even though more than one QTL may exist (Wright and Kong, 1997).
These were formulated as concretely as possible.
Here the controller synthesis is based on user-specified peak overshoot and rise time and has been formulated as a single objective optimization problem.
The FDA has granted IND status, orphan drug and fast-track statuses to OrbeShield, which has been formulated as a single product consisting of two tablets for p.o. administration to patients with GI ARS; one tablet is intended to release BDP in the proximal and the other in the distal portions of the GI tract [ 25].
Previously, this problem has been formulated as a single-objective optimization problem, in which the objective is to minimize the total number of clients that are without QoS.
However, de novo engineered circuits have been designed to perform a single task, and optimization based designs in Synthetic Biology have been formulated as problems with a single objective.
In this paper the optimal design of the exchanger has been formulated as a geometric programming with a single degree of difficulty.
These functions are formulated as a single objective optimization problem using fuzzy set theory.
The optimization problem is formulated as a single criterion mixed-integer nonlinear discrete combinatorial task.
This final version cannot even be formulated as a single problem for which an optimal mixed integer linear programming algorithm exists.
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