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Researchers in Colorado revealed at a European fertility conference that embryos from mice that had been fed a high protein diet showed a failure to implant in the womb.
Moreover McClean and colleagues investigated GIP antagonism in mice that had been fed a high fat diet for 160 days prior to the treatment with a GIP antagonist.
Haematoxylin and eosin staining revealed typical plaque morphology in ApoE−/− aortic cross-sections from mice which have been fed a high fat diet for 4 months (Fig. 1f).
In another study a β-cell knockout was compared with whole body knockout mice that had been fed a high fat diet.
Animals in all groups had been fed a high fat diet for eight weeks prior to the study and continued to eat the same food for the duration of the six-week study.
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Based on previous observations, Yi et al examined the brains of mice that had been fed a high-fat diet (HFD) for ∼16 weeks for signs of inflammation.
Citing a study in which mice became obese after being fed a high fat diet, Ms Hill explained their diet caused the microbes in their gut to change.
To induce atherosclerosis in mice, ApoE knockout mice were fed a high cholesterol diet for 4 months.
After acclimatization, at the age of 9-10 weeks (body weight 18.1 ± 1 g), the mice were fed a high fat, Western type experimental diet for six weeks.
C57BL/6J male mice were fed a high fat diet and were gavaged with a vehicle once or twice daily for 9 weeks.
Another group was fed a high fat diet with Atlantic salmon from which the PCBs and chlorinated pesticides were removed.
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