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Jim Meer, director of fruit and vegetable supplier Barfoots, said: "The 2014 season has been extremely challenging for the supply of pumpkins into the UK market.
Joe Earley, a spokesman for the Fox network, said: "The movie area has been extremely challenging for this network since it began, and even for those networks that have enjoyed success with original movies these are tough times.
Comparing array data between species has been extremely challenging for numerous technical and biologic reasons.
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Markets deteriorated markedly in the first quarter, he said, and the operating environment "continued to be extremely challenging for the entire industry".
"This was extremely challenging for the trust as it was far below the cost of the pilot 111 services that the trust had experience of, and was substantially below the level of cost that the trust had modelled as its future 111 service proposals".
He wasn't afraid of tackling whatever felt right to him – whether it was The Judas Tree, which was extremely challenging for everyone, or The Prince of the Pagodas, which threw some people because he went back to a classical language they didn't expect from him".
The process is extremely challenging for shale reservoirs due to large uncertainties including reservoir heterogeneity, wide range of permeability, gas desorption, and fracture properties.
However, surface modification, particularly at low temperature, is extremely challenging for high strength materials such as stainless steel and has not been investigated comprehensively so far.
McIntosh referenced how social interaction can be extremely challenging for people with autism.
In some cases, the abuse seems embedded so deeply on the cellular level that it is extremely challenging for these women to access their hearts' invincibility.
It is extremely challenging for a product to stand out from the crowd to even become considered by a grocer ― we're going to use Whole Foods as an example ― and once it gets there, it only gets more difficult.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com