Sentence examples for been extensively implicated from inspiring English sources
Aberrant activation of oncogenic signal transducer and activator of transcription 3 (STAT3) protein signaling pathways has been extensively implicated in human cancers.
In addition to their classical transport function, NPCs have now been extensively implicated in transcriptional gene regulation and in DNA damage repair via interactions with the underlying chromatin.
The amygdala was used because it has been extensively implicated in anxiety-like behavior.
The tachykinins have been extensively implicated in the initiation and progression of lung disease processes such as bronchitis and asthma [16] [19].
Additionally, miR-124 has also been extensively implicated in glioma pathogenesis [13], [23] although the association with extracellular matrix proteins expression presented in our study is completely novel, necessitating further exploration of their biological relevance.
While not included in the Venn-restricted data set, we also assessed the presence of Wnt family members and BMP antagonists (Figure 9C) since these signaling pathways have been extensively implicated in the early phases of cardiac specification.
However, the Ae. albopictus mosquito was extensively implicated in CHIKV transmission during the 2005 06 outbreak in Réunion Island (1 ).
After its discovery as a key controller of metabolic function, leptin has been later extensively implicated in additional functions including important modulatory activities on the innate and adaptive immune response.
Age-related changes to subcutaneous tissue have been extensively documented and implicated as affecting facial appearance [13] [16], and probably accounted for some of the remaining variation in the data.
Whereas the induction of cell proliferation by arsenite has been extensively studied, the events implicated in regulating the apoptosis of skin cells exposed to arsenite remain largely unknown.
The overall functional, structural, and biochemical alterations in ageing muscle have been extensively studied, but the molecular mechanisms implicated remain to be specified.
