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Interestingly, the role of several markers of hormonal impregnation such as male premature pattern baldness, history of acne in childhood or teenage years and hypofertility/infertility have also been explored in prostate cancer pathogenesis with contradictory results [ 48- 51].
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New agents include nedaplatin, a cisplatin-like compound registered in Japan and active in NSCLC (Judson et al, 1997), and satraplatin, an orally available drug with dose-limiting toxicity similar to that of carboplatin currently being explored in prostate cancer.
Rapalogs have been explored in pilot studies in prostate cancer, and PI3K and mTORC1/2 kinase inhibitors are now in early-stage clinical trials across tumor types.
This study defines the involvement of CB2-mediated signalling in the in vivo and in vitro growth inhibition of prostate cancer cells and suggests that CB2 agonists have potential therapeutic interest and deserve to be explored in the management of prostate cancer.
Gene expression profile of human ABC transporters was explored in cancerous and noncancerous prostate tissue by means of TaqMan Low Density Arrays (TLDA).
Thus, the model includes the essential effects of androgens with minimum complexity, and the qualitative effects of androgens on the prostate epithelium can be explored in a minimal formal setting.
Potential uptake of the scFv by androgen-dependent prostate cancer cells will be explored in future studies.
This issue will be explored in 5.3.
Newtonian mechanics is explored in each section.
A role for heat shock protein 90 inhibitors in prostate cancer has been explored only in the context of systemic treatment of refractory metastatic disease.
Three techniques for using MR images to improve prostate biopsies have been explored thus far: in-bore, cognitive registration, and software registration-based MRI-TRUS fusion.
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