Sentence examples for been explored in large from inspiring English sources
For example, localized, catheter-mediated delivery to the liver has been explored in large animal models [3] and may have a superior safety profile compared to the systemic delivery method used in mice.
Thermal effect on the brain and the surrounding structures is one of them, but to date has not been explored in large series nor highlighted as potentially harmful.
However, this issue has never been explored in large series, and our data provide the first evidence of an independent association between hypoglycemia and QTc prolongation in a large epidemiologic study on type 1 diabetes.
In addition, products of elastin degradation may act as angiogenic triggers through upregulation of MT1-MMP leading to sprouting and tube formation of endothelial cells Finally, vasa vasorum may also originate from the luminal endothelium, but this has not been explored in large size arteries such as the aorta.
The association between long-term exposure to ambient air pollution and PD/AD has not been explored in large-scale epidemiologic studies, with the exception of three studies that examined the relationship between airborne metal exposures and PD and showed evidence suggestive of the harmful effects of manganese (Finkelstein and Jerrett 2007; Willis et al. 2010) and mercury (Palacios et al. 2014).
However, the clinical benefit of a fiberoptic endoscopic evaluation of swallowing approach to nutrition on other outcomes in recentlyextubated patients with neurologic disorders has not been explored in larger prospective studies.
Whether kisspeptins will be the future agent to trigger ovulation remains to be explored in large clinical trials.
Gene regulatory networks are explored in large scale in gene deletion studies [ 11- 13] and transcription factor binding experiments [ 14], but various uncertainties relate to those studies.
The mechanisms of the decrease in SOS, and the way by which it can be prevented, for instance by physical therapy [23] or by other physical approaches for prevention of bone loss [24] can only be explored in larger prospective trials.
