While such delivery has been explored in cells, the step of demonstrating cytoplasmic delivery in tumors in an animal had not been taken before the work we report here.
A trip of a lifetime following a diagnosis of motor neurone disease is explored in Cell, by Smoking Apples and Dogfish, which is at the Mumford theatre in Cambridge on Saturday night as part of a longer tour.
Our research provides a comparative basis for prospecting more specific terpene synthases genes for -elatol and other commercially relevant terpenes, which could be explored in cell factories.
These reactions are increasingly being explored in cell-based and in vivo applications.
Although COD has been explored in various cell types, such as HaCaT cells, hippocampal cells, Chinese hamster ovary cells, fibroblasts and kidney epithelial cells, the apoptotic mechanism is largely unclear.
The dynamics of cytoskeleton and endomembrane reorganization during pathogen attack have been explored in living cells through studies of GFP-tagged cell components [ 20- 24].
Furthermore, resveratrol and apigenin control the activity of BCL2 in inducing apoptosis in cancer cells [ 62, 63], but the effect of these flavonoids has not been explored in PHBE cells or in in vivo models for RSV infection.
The toxic responses of OPs on cellular and molecular level have been explored in cultured cells using standard endpoints of cytotoxicity and genotoxicity [5], [11].
The function of H19 has been explored in mice and cell lines by using knockdown and transgenic approaches.
The use of metformin to counteract or prevent tamoxifen resistance has also been explored in breast cancer cell lines with positive results.
